Table 1.
The baseline data for IgAN patients with lower and higher ST6GAL1 levels.
| Characters | Mean ± SD or n (%) | p | |
|---|---|---|---|
| Low ST6GAL1 (n < 6412 pg/mL) | High ST6GAL1 (n > 6412 pg/mL) | ||
| Gender (M/F) | 44 (49)/46 (51) | 47 (52)/43 (48) | 0.65 |
| Age (mean ± SD, year) | 40.01 ± 13.11 | 39.84 ± 13.63 | 0.93 |
| SBP (mmHg) | 130.43 ± 17.81 | 134.84 ± 17.4 | 0.09 |
| DBP (mmHg) | 80.59 ± 11.69 | 83.47 ± 11.72 | 0.1 |
| BMI (kg/m2) | 24.14 ± 4.21 | 25.28 ± 3.35 | 0.06 |
| Hemoglobin (g/L) | 131.58 ± 18.13 | 133.08 ± 20.13 | 0.6 |
| Serum albumin (g/L) | 37.04 ± 5.06 | 37.03 ± 5.03 | 0.98 |
| Triglyceride (mmol/L) | 1.69 ± 1 | 2.78 ± 2.66 | 0.001 |
| Serum creatinine (μmol/L) | 87.47 ± 47.81 | 100.96 ± 47.78 | 0.06 |
| eGFR (mL/min/1.73 m2) | 102.18 ± 51.62 | 84.81 ± 33.6 | 0.008 |
| Uric acid (μmol/L) | 357.21 ± 97.52 | 401.99 ± 107.09 | 0.004 |
| Serum IgA (mg/dL) | 313.22 ± 121.19 | 573.74 ± 418.8 | 0.001 |
| Serum IgG (mg/dL) | 1051.3 ± 261.4 | 889.42 ± 420.69 | 0.003 |
| Serum IgM (mg/dL) | 119.39 ± 64.23 | 113.31 ± 54.85 | 0.513 |
| Serum IgE (mg/dL) | 66.4 ± 167.19 | 158.64 ± 495.06 | 0.11 |
| Serum C3 (mg/dL) | 86.63 ± 15.6 | 94.47 ± 17.86 | 0.003 |
| Serum C4 (mg/dL) | 21.95 ± 5.95 | 25.15 ± 8.48 | 0.005 |
| Proteinuria (mg/d) | 1409.83 ± 1373.14 | 2116.87 ± 1955 | 0.006 |
| Urine RBC (/HP) | 35.93 ± 61.24 | 80.58 ± 257.26 | 0.11 |
| Oxford classification | |||
| M score (M0/M1) | 11 (12)/79 (88) | 10 (11)/80 (89) | 0.82 |
| E score (E0/E1) | 53 (59)/ 37 (41) | 52 (58)/38 (42) | 0.89 |
| S score (S0/S1) | 44 (49)/46 (51) | 28 (31)/62 (69) | 0.02 |
| T score (T0/T1/T2) | 35 (39)/50 (56)/5 (5) | 27 (30)/50 (55)/13 (15) | 0.15 |
| C score (C0/C1/C2) | 23 (26)/54 (60)/13 (14) | 32 (36)/50 (55)/8 (9) | 0.25 |
BMI, body mass index; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; IgAN, immunoglobulin A nephropathy; RBC, red blood cell; SBP, systolic blood pressure; SD, standard deviation.