Author response image 1. Disinhibiting the standard and deviant stimulus leads to differential increase in responses to standard and deviant tones.

A. Population firing rate of excitatory neurons in response to standard stimuli (gray) or to deviant stimuli (red) without disinhibition (dark colors) and with disinhibition (suppression of the total inhibitory population) (light colors). All responses are normalized to the response to the fourth non-disinhibited post-novelty stimulus of one instantiation of the model. B. Difference between firing rates with and without disinhibition from panel A in response to standard (gray) and deviant (red) stimuli. Error bars correspond to the standard deviation across three model instantiations.