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. 2021 Oct 15;131(20):e147116. doi: 10.1172/JCI147116

Figure 7. Conditional transgenic mice expressing PDGF-BB in preosteoclasts recapitulate aging-associated artery phenotype.

Figure 7

PWV (A), systolic BP (B), diastolic BP (C), and mean BP (D) were measured in young (3- to 4-month old) and old (>18 months old) PdgfbcTG and WT littermates. PWV (E), systolic BP (F), diastolic BP (G), and mean BP (H) were measured in old (>18 months old) male and female PdgfbcTG and WT littermates. n = 5 to 14. Data are mean ± SEM, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 as determined by 1-way ANOVA with Bonferroni post hoc test.