Table 1.
Characteristics of the weighted NEO study population
| All n = 6334 | |
|---|---|
| General patient characteristics | |
| Age (year) | 56 (6) |
| Sex (% women) | 55 |
| Education (% high) | 46 |
| Body mass index (kg/m2) | 26 (4) |
| History of cardiovascular disease (%) | 6 |
| Antihypertensive medication (% users) | 23 |
| Exposure variables | |
| Systolic blood pressure (mmHg)a | 134 (19) |
| Diastolic blood pressure (mmHg)a | 85 (12) |
| Carotid intima-media thickness (mm) | 0.62 (0.09) |
| Popliteal artery vessel wall thickness (mm)b | 0.53 (0.05) |
| Aortic pulse wave velocity (m/s)b | 6.56 (1.30) |
| OA phenotypes | |
| Clinical hand OA (%) | 8 |
| Clinical knee OA (%) | 10 |
| Structural knee OA (%)c | 12 |
| Bone marrow lesions (%)c | 32 |
| Effusion (%)c | 12 |
Results are based on analyses weighted towards the BMI distribution of the general population (n = 6334). Numbers represent mean (s.d.) unless otherwise specified. a>Blood pressure was adjusted for antihypertensive medication use when applicable (systolic +15 mmHg, diastolic +10 mmHg). bPopliteal VWT (n = 1095) and PWV (n = 2382) measurements are performed in MRI subpopulations. cPercentage of participants who underwent knee MRI (n = 1285).