Table 3.
Multivariate predictors of LV remodelling
| Full model |
Final model |
|||
|---|---|---|---|---|
| Predictors of LVMI | β coefficient ± SE | P | β coefficient ± SE | P |
| Doppler peak gradient, per 5 mmHg | 0.42 ± 0.49 | 0.2 | — | |
| SBP, per 5 mmHg | 0.63 ± 0.42 | 0.045 | 0.61 ± 0.37 | 0.034 |
| ULE-SBP gradient, per 5 mmHg | 0.18 ± 0.19 | 0.2 | ||
| Aortic isthmus ratio | −23.6 ± 14.2 | <0.001 | −28.3 ± 14.1 | <0.001 |
| Presence of collateral vessels | 2.54 ± 4.59 | 0.6 | ||
| Predictors of LV e′ | ||||
| Doppler peak gradient, per 5 mmHg | −0.18 ± 0.06 | 0.022 | −0.19 ± 0.02 | 0.016 |
| SBP, per 5 mmHg | −0.33 ± 0.39 | 0.4 | ||
| ULE-SBP gradient, per 5 mmHg | 0.13 ± 0.24 | 0.3 | ||
| Aortic isthmus ratio | 3.26 ± 1.36 | 0.007 | 3.11 ± 1.10 | 0.014 |
| Presence of collateral vessels | −2.41 ± 3.17 | 0.2 | ||
| Predictors of LV E/e′ | ||||
| Doppler peak gradient, per 5 mmHg | 0.14 ± 0.26 | 0.4 | ||
| SBP, per 5 mmHg | 0.30 ± 0.31 | 0.1 | ||
| ULE-SBP gradient, per 5 mmHg | 0.27 ± 0.32 | 0.3 | ||
| Aortic isthmus ratio | −12.9 ± 6.44 | 0.009 | −13.4 ± 6.67 | 0.008 |
| Presence of collateral vessels | 2.91 ± 4.22 | 0.3 | ||
| Predictors of LVGLS | ||||
| Doppler peak gradient, per 5 mmHg | −0.49 ± 0.51 | 0.2 | ||
| SBP, per 5 mmHg | −0.52 ± 0.21 | 0.002 | 0.53 ± 0.11 | 0.001 |
| ULE-SBP gradient, per 5 mmHg | −0.35 ± 0.42 | 0.4 | ||
| Aortic isthmus ratio | 1.43 ± 0.25 | 0.028 | 1.51 ± 0.42 | 0.005 |
| Presence of collateral vessels | −1.16 ± 1.72 | 0.6 | ||
Regression models were adjusted for age, sex, LV ejection fraction, history of hypertension, and age at the time of initial COA repair.
E, mitral inflow Doppler early velocity; e′, mitral annular Doppler tissue early velocity; LV, left ventricle; LVGLS, left ventricular global longitudinal strain; LVMI, left ventricular mass index; SBP, systolic blood pressure; SE, standard error; ULE, upper-to-lower extremity.