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Risk of bias summary: review authors' judgments about the risk of bias item for each included study. The items in the Systematic Review Centre for Laboratory animal Experimentation (SYRCLE) risk of bias assessment were scored with “yes” indicating low risk of bias, “no” indicating high risk of bias, or “unclear” indicating that the item was not reported, resulting in an unknown risk of bias. Green: low risk of bias; yellow: unclear risk of bias; red: high risk of bias.
