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. 2021 Oct 12;27(10):1797–1805. doi: 10.1038/s41591-021-01497-1

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 7 — a) Summary of neurotoxicity events in the 5 patients who had any reported neurotoxicity AE. Note: Patient 3 had a not resolved event because the event was still ongoing when patient died due to disease progression 2.3 months after AUT03 infusion. b) Serum cytokine levels in patient 001 who experienced encephalopathy 5 days after a 0.3×10⁶cell/kg dose of AUTO3 infusion, the encephalopathy was considered likely related to the prior infusion of intrathecal methotrexate and unlikely related to AUTO3.