Figure 5 (Case 3):

While this neoplasm presented as a solitary liver mass, one can appreciate the multinodular appearance and entrapped hepatocytes within the neoplasm (A). At higher magnification, the solid trabecular areas with microcystic/follicular patterns and the biphasic cytology are evident (B). High power shows solid nested areas resembling well-differentiated neuroendocrine neoplasm (C). More fibrotic areas demonstrate more angulated glands merging with the microfollicular areas (D). The neoplasm is diffusely immunoreactive for inhibin (E), demonstrates patchy labeling for synaptophysin (F), and multifocal patchy labeling for cytokeratin 19 (G), and focally contains albumin mRNA transcripts (H).