Table 3.

Measures of blood product use and hemostatic agent administration pre life-threatening bleeding

	Overall (N = 449)		Trauma (N = 207)		Operative (N = 153)		Medical (N = 89)
Measure	Obs	M [Q1–Q3] n (%Obs)	Obs	M [Q1–Q3] n (%Obs)	Obs	M [Q1–Q3] n (%Obs)	Obs	M [Q1–Q3] n (%Obs)	P
Any red blood cells	449	186 (41.4)	207	86 (41.5)	153	60 (39.2)	89	40 (44.9)	0.68
Red blood cells (mL/kg)a, c	186	20.2 [11.2–41.5]	86	17.9 [10.6–28.8]	60	35.1 [15.3–60.0]	40	18.9 [11.9–31.9]	<.01
Any plasmaa, b	449	81 (18.0)	207	14 (6.8)	153	38 (24.8)	89	29 (32.6)	<.01
Plasma (mL/kg)a, b	81	13.1 [6.0–29.7]	14	5.2 [3.9–10.4]	38	18.8 [9.4–41.0]	29	18.0 [7.6–36.9]	<.01
Any plateletsa, b	449	69 (15.4)	207	6 (2.9)	153	38 (24.8)	89	25 (28.1)	<.01
Platelets (mL/kg)c	69	12.3 [6.7–22.5]	6	17.0 [6.8–22.5]	38	16.8 [8.3–33.3]	25	8.3 [5.4–12.3]	0.01
Any cryoprecipitatea, b	449	31 (6.9)	207	2 (1.0)	153	22 (14.4)	89	7 (7.9)	<.01
Cryoprecipitate (mL/kg)	31	5.17 [2.9–15.2]	2	16.0 [2.9–29.1]	22	5. 9 [3.3–15.2]	7	4.7 [2.2–8.8]	0.54
Any blood product	449	212 (47.2)	207	87 (42.0)	153	77 (50.3)	89	48 (53.9)	0.11
Total blood product (mL/kg)a	212	23.6 [12.0–55.1]	87	18.1 [10.7–31.4]	77	37.2 [16.1–80.3]	48	25.1 [13.2–54.7]	<.01
Any crystalloida, b	449	282 (62.8)	207	110 (53.1)	153	107 (69.9)	89	65 (73.0)	<.01
Crystalloid (mL/kg)	282	25.0 [12.4–41.4]	110	27.1 [14.3–41.5]	107	24.5 [12.0–33.8]	65	25.2 [12.4–55.6]	0.24
Any colloida, b	449	64 (14.3)	207	8 (3.9)	153	42 (27.5)	89	14 (15.7)	<.01
Any tranexamic acida, c	449	20 (4.5)	207	4 (1.9)	153	15 (9.8)	89	1 (1.1)	<.01
Any aminocaproic acida	449	14 (3.1)	207	0 (0.0)	153	12 (7.8)	89	2 (2.2)	<.01
Any recombinant factor VIIaa	449	10 (2.2)	207	1 (0.5)	153	7 (4.6)	89	2 (2.2)	0.03

Abbreviations M median; N number; P probability; Q quartile.

^aP < 0.017 trauma v operative

^bP < 0.017 trauma v medical

^cP < 0.017 operative v medical