TABLE 1.

Compositions of the peptide and mixotope used as solid-phase antigens in ELISAs of IgM against EBV^a

Antigen	Sequence
VCA p18	A V D T G S G G G G Q P H D T A P R G A R K K Q
	A V D T             Q   H D T A   R G A R K K Q
MIXO (P,G)	G S G G G G   P         P
	G I E S             N   G E S G   K S G K R R N

^aEquimolar amounts of the appropriate subsets of amino acids (shown vertically for the mixotope) were introduced in each degenerate position during the synthesis. Theoretically, this produced sets of peptides containing 65,536 closely related combinatorial sequences.