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. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Trends Endocrinol Metab. 2021 Sep 3;32(11):916–928. doi: 10.1016/j.tem.2021.08.004

Figure 1. The effect of nutrient metal on immune cell function.

Figure 1.

A graphical representation showing how nutrient metal (zinc = Zn, iron = Fe, manganese = Mn, copper = Cu) excess and deplete conditions alter neutrophil and macrophage antimicrobial functions in response to pathogens. Arrows represent conditions that enhance and blocked lines represent conditions that impair the indicated immune cell function. No effect (NE) on phagocytosis by neutrophils has been observed in copper deplete conditions. Created with BioRender.com.