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. 2021 Oct 8;39(11):1343–1354. doi: 10.1007/s40273-021-01091-w

Table 3.

Base-case analysis deterministic resultsa

Vericiguat + PSoCT PSoCT Difference
Total LYs per patient 4.18 3.82 0.35
Alive, prior to HFH 2.93 2.54 0.38
Alive, during or post HFH 1.25 1.28 −0.03
Total QALYs per patient 3.34 3.05 0.28
Alive, prior to HFH 2.34 2.04 0.31
Alive, during or post HFH 0.99 1.02 −0.02
Number of events per 1000 patients
HFH 681 700 −19
CV mortality 427 440 −13
Total costs per patient $60,228 $36,907 $23,322
Drug acquisition $25,686 $3,160 $22,526
HFH $7093 $7295 −$202
Routine care $19,430 $18,337 $1093
Terminal care $8020 $8,115 −$95
Incremental cost per QALY gained per patient $82,448
Incremental cost per LY gained per patient $65,988

CV cardiovascular, HFH heart failure hospitalization, LYs life-years, PSoCT prior standard-of-care therapies, QALYs quality-adjusted life-years

aValues were rounded to the nearest number