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. 2021 Oct 14;116(1):60. doi: 10.1007/s00395-021-00901-8

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Effects of RIPC/cRIPC plasma on in-vitro angiogenesis. A representative images of HUVEC cultures that were incubated with Control, RIPC and cRIPC plasma. Upper panel, original images. Lower panel, graphical results of the analysis using the angiogenesis analyzer tool of the Image J software 1.41 (NIH) [4]. Scale bars depict 300 µm. B effects of RIPC and cRIPC plasma on key parameters of tube formation in-vitro. Control values were set to 1. Horizontal lines show the mean. *P < 0.05; one-sample T test. ^§P < 0.05; ^§§P < 0.01; two-tailed T test