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. 2021 Aug 9;39(11):1243–1269. doi: 10.1007/s40273-021-01065-y

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© The Author(s) 2021, corrected publication 2021

Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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Fig. 1. — Article ranking based on the total suitability scores of the R&D cost estimation. † Excluding the factor(s) that is (are) plotted separately. †† Part of the “Drug sample characteristic group”. ††† Part of the “Possible sources of variation in R&D costs group”. ‡ Part of the “Monetary values group”. The number next to the reference represents the ranking of the estimation in accordance with the value of the suitability score. Estimations that share the same suitability score have the same ranking. Source: Authors’ elaboration