Table 1. Dynamic changes of the hepatic function indexes in the survivor and non-survivor patients with EHS.
| Overall (n=186) | Survivor (n=164) | Non-survivor (n=22) | p | |
|---|---|---|---|---|
| TBIL in µmol/L | ||||
| Ad | 15.85 [10.10, 29.40] | 14.75 [9.80, 25.47] | 29.90 [14.98, 118.08] | 0.002 |
| 24 h | 27.10 [15.45, 55.65] | 23.70 [15.07, 47.85] | 95.60 [53.53, 176.45] | <0.001 |
| 2 d | 36.65 [17.20, 87.28] | 28.90 [15.70, 55.70] | 176.00 [96.05, 198.20] | <0.001 |
| 3 d | 32.60 [17.60, 97.10] | 24.50 [16.40, 59.75] | 233.45 [166.45, 373.32] | <0.001 |
| 5 d | 23.85 [10.20, 83.05] | 18.90 [9.80, 36.10] | 390.30 [328.10, 422.00] | <0.001 |
| 7 d | 20.90 [12.20, 73.60] | 16.10 [9.70, 28.85] | 400.20 [251.33, 424.70] | <0.001 |
| ALT in U/L | ||||
| Ad | 34.50 [20.00, 222.75] | 32.00 [19.00, 149.50] | 170.50 [61.50, 1,648.25] | <0.001 |
| 24 h | 234.50 [56.25, 956.25] | 174.50 [47.25, 652.00] | 1,530.00 [792.75, 2,649.50] | <0.001 |
| 2 d | 383.00 [134.00, 1,389.50] | 355.00 [134.00, 1,112.50] | 1,660.00 [460.00, 3,474.00] | 0.017 |
| 3 d | 468.00 [164.25, 1,431.00] | 407.50 [144.75, 1,094.75] | 2,573.50 [1,228.50, 4,911.50] | <0.001 |
| 5 d | 373.50 [129.00, 666.00] | 348.00 [110.00, 609.00] | 488.00 [370.50, 870.50] | 0.077 |
| 7 d | 192.00 [106.00, 309.00] | 205.00 [94.50, 312.00] | 148.50 [115.75, 217.50] | 0.726 |
| AST in U/L | ||||
| Ad | 66.50 [34.75, 228.00] | 62.00 [33.50, 163.50] | 356.00 [110.00, 1,645.00] | <0.001 |
| 24 h | 214.00 [60.00, 751.75] | 166.00 [57.00, 559.00] | 2,545.00 [631.00, 5,690.00] | <0.001 |
| 2 d | 278.00 [91.50, 947.50] | 250.00 [89.00, 625.00] | 2,635.00 [421.75, 5,159.00] | <0.001 |
| 3 d | 183.00 [70.50, 568.50] | 162.00 [66.50, 462.00] | 1,629.50 [359.50, 5,276.75] | 0.001 |
| 5 d | 118.50 [59.00, 219.00] | 116.00 [56.00, 190.00] | 220.00 [101.00, 355.00] | 0.058 |
| 7 d | 67.50 [39.25, 101.50] | 58.50 [34.50, 80.75] | 102.50 [75.00, 126.50] | 0.003 |
| INR | ||||
| Ad | 1.29 [1.09, 1.76] | 1.24 [1.09, 1.47] | 3.22 [1.86, 4.82] | <0.001 |
| 24 h | 1.29 [1.09, 1.70] | 1.19 [1.07, 1.54] | 2.76 [2.20, 3.28] | <0.001 |
| 2 d | 1.14 [1.04, 1.65] | 1.10 [1.02, 1.32] | 2.82 [2.04, 3.59] | <0.001 |
| 3 d | 1.05 [0.97, 1.70] | 1.02 [0.96, 1.21] | 3.10 [2.07, 3.53] | <0.001 |
| 5 d | 1.01 [0.93, 1.21] | 0.98 [0.93, 1.11] | 3.02 [2.08, 4.04] | <0.001 |
| 7 d | 1.07 [0.99, 1.33] | 1.03 [0.98, 1.11] | 2.38 [1.53, 2.57] | <0.001 |
d, day.