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. 2021 Oct 14;11:20421. doi: 10.1038/s41598-021-99961-y

Table 2.

FH ALERT’s pilot initiative key results.

Period of time: 12 weeks Absolute values
Cholesterol examinations 75,431
Number of patients in whom examinations were performed 60,812
Patients tested twice 7479
Patients tested three times 2679
Patients tested four times 274
Patients tested five times or more 145
Alert letters, n (%) 3512 (4.66)
Number of patients triggering Alert letters 2846
Distribution of alerts
Category I
 Adults with probable suspicion 3177
 Children with strong suspicion 154
 Sum, n (%) 3331 (94.85)
 Thereof LDL C, n (%) 838 (25.16)
 Thereof TC, n (%) 2493 (74.84)
Category II
 Adults with strong suspicion, n (%) 181 (5.15)
 Thereof LDL C, n (%) 47 (25.97)
 Thereof TC, n (%) 134 (74.03)
Age
 Patients < 18 years, n (%) 154 (4.38)
 Patients ≥ 18 ≤ 60 years, n (%) 3,358 (95.62)
 Average age (total/ female/male, years) 48/50/47
Acceptance and feedback
Total number of clients of MCC Weiden GmbH, n (%) 1411 (100)
Clients with Opt-out, n (%) 200 (14.17)
Alerted clients
 Clients with alert letters, n (%) 462 (32.74)
 Alert letters per client (total/alerted clients) 2.49/7.60
 ≥ 10 alert letters (Opt-in, cum.), n (%) 121 (26.19)
 ≥ 5 ≤ 9 alert letters (Opt-in, cum.), n (%) 48 (10.39)
 ≥ 3 ≤ 4 alert letters (Opt-in, cum.), n (%) 37 (8.01)
 Positive reaction by caller, n (%) 370 (69.94)
 Negative reaction by caller, n (%) 38 (7.18)
 Undifferentiated reaction by caller, n (%) 121 (22.87)
FH score
 New visitors/recurring visitors 101/31
 Completed questionnaires 88
 Questionnaires > 3 45
Genetic testing
Requested genetic test kits 93
Returned genetic test kits, n (%) 26 (27.96%)

Data describes general information, distribution of alerts, acceptance, feedback, and genetic testing.