. 2021 Oct 14;11:20455. doi: 10.1038/s41598-021-99836-2

Table 2.

Varying DNA methylation target CpG site and related genes.

CpG site ^a	Gene Symbol	Chr	Distance to TSS	Methylation level (Mean ± SD)		difference ^b	P value	FDR
CpG site ^a	Gene Symbol	Chr	Distance to TSS	GDM (80)	Control (80)	difference ^b	P value	FDR
chr20: 37274257	ARHGAP40	20	( +) 43,681	0.601 ± 0.046	0.584 ± 0.048	0.017	0.015	0.033
chr5: 43487508	C5orf34	5	( +) 27,765	0.456 ± 0.078	0.414 ± 0.105	0.042	0.012	0.044
chr7: 157130156	DNAJB6	7	( +) 446	0.010 ± 0.006	0.012 ± 0.005	0.002	0.013	0.033
chr7: 157130085	DNAJB6	7	( +) 375	0.006 ± 0.003	0.007 ± 0.004	0.001	0.018	0.031
chr11: 101980999	YAP1	11	( −) 192	0.009 ± 0.003	0.007 ± 0.003	0.002	0.001	0.013
chr11: 101981060	YAP1	11	( −) 131	0.011 ± 0.004	0.012 ± 0.004	0.001	0.028	0.036
chr21: 34775358	IFNGR2	21	( +) 157	0.024 ± 0.038	0.036 ± 0.039	0.012	0.012	0.044
chr22: 42466321	NAGA	22	( +) 525	0.049 ± 0.014	0.055 ± 0.016	0.006	0.008	0.052
chr14: 68167324	RDH12	14	( −) 1278	0.273 ± 0.009	0.270 ± 0.009	0.003	0.019	0.027
chr14: 68167386	RDH12	14	( −) 1216	0.314 ± 0.009	0.311 ± 0.013	0.003	0.042	0.045
chr15: 89438648	HAPLN3	15	( +) 209	0.011 ± 0.004	0.013 ± 0.006	0.002	0.048	0.048
chr14: 24837915	NFATC4	14	( −) 288	0.015 ± 0.003	0.014 ± 0.003	0.001	0.018	0.031
chr2: 191879104	STAT1	2	( −) 128	0.008 ± 0.003	0.009 ± 0.005	0.001	0.037	0.043

Abbreviation: Chr chromosome, TSS transcription start site and strand; CpG site ^a: position on chromosome; difference ^b: the difference of the mean methylation level in the GDM group to that in the Control group.