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. 2021 Oct 14;11:20455. doi: 10.1038/s41598-021-99836-2

Table 3.

The AUC and cut-off value of CpG site DNA methylation.

CpG site Gene Symbol Cut-off value Sensitivity Specificity AUC 95% CI P value
For GDM
chr20: 37274257 ARHGAP40 0.600 0.550 0.638 0.594 0.506–0.682 0.040*
chr5: 43487508 C5orf34 0.420 0.775 0.475 0.602 0.514–0.691 0.026*
chr14: 24837915 NFATC4 0.014 0.713 0.525 0.628 0.541–0.715 0.005*
chr14: 68167386 RDH12 0.315 0.475 0.750 0.601 0.513–0.689 0.028*
chr14: 68167324 RDH 12 0.278 0.550 0.563 0.589 0.501–0.677 0.051
chr11: 101980999 YAP1 0.009 0.525 0.713 0.650 0.566–0.735 0.001*
For Control
chr15: 89438648 HAPLN3 0.013 0.688 0.532 0.597 0.509–0.688 0.034*
chr7: 157130156 DNAJB6 0.013 0.747 0.463 0.608 0.521–0.696 0.019*
chr2: 191879104 STAT1 0.008 0.663 0.525 0.583 0.495–0.672 0.069
chr7: 157130085 DNAJB6 0.004 0.506 0.688 0.593 0.505–0.681 0.043*
chr11: 101981060 YAP1 0.014 0.550 0.575 0.582 0.494–0.670 0.074
chr21: 34775358 IFNGR2 0.028 0.671 0.566 0.614 0.533–0.708 0.014*

*P < 0.05.