Table 4.

ADRs in primary and non-primary medical institutions lead to results.

Primary health institutions	Yes OR (95% CI)	No OR (95% CI)
Gender (refer to male)
Female	0.984 (0.880–1.021)	1.078** (1.034–1.124)
Age (refer to 18–35)
0–6	0.804* (0.647–0.999)	0.669** (0.598–0.749)
6–18	0.854 (0.701–1.041)	0.887 (0.780–1.009)
35–60	0.972 (0.870–1.087)	1.015 (0.952–0.082)
60–80	1.075 (0.960–1.204)	1.122** (1.052–1.196)
> 80	1.373* (1.140–1.654)	1.029 (0.935–1.133)
Number of diseases (refer to 1)
≥ 2	1.651** (1.449–1.881)	1.197** (1.139–1.259)
Polypharmacy (refer to no)
Yes	5.145** (2.862–9.248)	4.004** (3.502–4.579)
Type of drug (refer to chemical compound)
Chinese patent medicine	0.805** (0.736–0.880)	0.639** (0.596–0.685)
Imported and biological product	0.654* (0.453–0.943)	1.200** (1.107–1.302)
Past history (refer to no)
Yes	2.671** (1.870–3.813)	2.237** (2.036–2.459)
Unknown	1.068 (0.995–1.146)	1.246** (1.194–1.301)
Past behavior (refer to no)
Smoking and drinking	1.215** (1.090–1.354)	1.511** (1.408–1.623)
Allergy	1.620** (1.130–2.322)	1.092 (0.951–1.254)
History of illness and surgery	0.916 (0.614–1.368)	1.574** (1.408–1.760)
Medication (refer to oral)
Injection	1.938** (1.804–2.082)	1.188** (1.136–1.243)
Others	2.096** (1.627–2.701)	0.917 (0.799–1.054)
Time from medication to ADR (refer to < 3)
≥ 3	2.345** (2.073–2.653)	3.686** (3.539–3.839)
Season (refer to spring)
Summer	1.008 (0.912–1.114)	1.033 (0.976–1.093)
Autumn	1.145** (1.043–1.257)	1.099* (1.041–1.161)
Winter	1.350** (1.196–1.523)	1.186** (1.114–1.264)
ADRs occurrence (refer to first)
Again	0.505* (0.291–0.879)	1.011 (0.895–1.142)
New adverse reactions (refer to no)
Yes	1.325** (1.230–1.426)	0.872** (0.828–0.918)

OR odds ratio, CI confidence interval.

*p < 0.05, **p < 0.01.