Fig. 2.

Summary of treatment response, progression-free and overall survival. a Maximal change of tumor size from baseline assessed by the investigator per RECIST v1.1 (n = 38). The length of the bar represents maximal decrease or minimal increase in target lesion(s). # Unconfirmed partial response classified as stable disease. * Patient with target lesion(s) reduction over 30% but with new lesion(s) or progression of nontarget lesion(s). b Change of individual tumor burden over time from baseline assessed by the investigator per RECIST v1.1 (n = 38). c Progression-free survival by RECIST v1.1 of all 40 enrolled patients. d Overall survival by RECIST v1.1 of all 40 enrolled patients. No. number