Table 1.
Characteristics of Cases with Birdshot Chorioretinitis
| Characteristic | Result |
|---|---|
| Number cases | 207 |
| Demographics | |
| Age, median, years (25th 75th percentile) | 51 (45, 58) |
| Gender (%) | |
| Men | 39 |
| Women | 61 |
| Race/ethnicity (%) | |
| White, non-Hispanic | 92 |
| Black, non-Hispanic | 0 |
| Hispanic | 1 |
| Asian, Pacific Islander | 0 |
| Other | 0 |
| Missing | 7 |
| Uveitis History | |
| Uveitis course (%) | |
| Acute, monophasic | 1 |
| Acute, recurrent | 1 |
| Chronic | 95 |
| Indeterminate | 3 |
| Laterality (%) | |
| Unilateral | 0 |
| Unilateral, alternating | 0 |
| Bilateral | 100 |
| Ophthalmic examination | |
| Keratic precipitates (%) | |
| None | 100 |
| Anterior chamber cells (%) | |
| Grade 0 | 83 |
| ½+ | 11 |
| 1+ | 5 |
| ≥2+ | 0 |
| Anterior chamber flare (%) | |
| Grade 0 | 93 |
| 1+ | 6 |
| 2+ | 1 |
| ≥3+ | 0 |
| Iris (%) | |
| Normal | 100 |
| Intraocular pressure (IOP), involved eyes | |
| Median, mm Hg (25th, 75th percentile) | 15 (14, 18) |
| Proportion patients with IOP>24 mm Hg either eye (%) | 2 |
| Vitreous cells (%) | |
| Grade 0 | 13 |
| ½+ | 16 |
| 1+ | 36 |
| 2+ | 32 |
| 3+ | 3 |
| 4+ | 0 |
| Vitreous haze (%) | |
| Grade 0 | 49 |
| ½+ | 19 |
| 1+ | 21 |
| 2+ | 11 |
| ≥3+ | 0 |
| Chorioretinal lesion characteristics | |
| Lesion number (%) | |
| Unifocal (1 lesion) | 0 |
| Paucifocal (2–4) | 0 |
| Multifocal (≥5) | 96 |
| Missing | 4 |
| Lesion shape & character (%) | |
| Ameboid or serpentine | 0 |
| Oval or round | 96 |
| Placoid | 0 |
| Atrophic | 2 |
| Punctate | 0 |
| Wedge-shaped | 0 |
| Missing | 2 |
| Lesion location (%) | |
| Posterior pole involved | 68 |
| Mid-periphery and periphery only | 32 |
| Typical lesion size (%) | |
| <250 μm | 31 |
| 250–500 μm | 40 |
| >500 μm | 24 |
| Missing | 5 |
| Other features (%) | |
| Retinal vascular sheathing | 17 |
| Retinal vascular leakage | 33 |
| Choroidal neovascularization | 0 |
| Laboratory data (%) | |
| HLA-A29 positive* | 89 |
*
184 of 186 cases tested (99%) were positive.