Table 1.

Phenotypes of SURF1 KO mice identified in previous studies

Study no.	Mouse age	Sex	Behavioral/physiological test	Function tested	Change in SURF1 KO mice	References
1	3 months	F+M	rotarod test	motor skill	↓	18
2	6–7 months	M	Y-maze	working memory	↑	27
			object recognition	long-term memory	↑
			elevated maze	basal anxiety	↔
3	5–6 months	M	open field activity	basal activity	↔	19
			treadmill test	endurance capacity	↓↓
			grip strength	muscle strength	↓
4	28 months	F	grip strength	muscle strength	↔	23
			rotarod test	motor skill	↔
			sleep/wake pattern	basal activity	↔
			open field activity	basal activity	↔
5	3 months	F+M	treadmill test	endurance capacity	↔	20

F, female; M, male. ↓, decrease; ↑, increase; ↔, no differences; the number of arrows indicate the degree of changes.