Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 14;23:151–162. doi: 10.1016/j.omto.2021.09.002

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Immune infiltration is the hallmark of the extinction group

(A) Tree map (hierarchical heatmap) depicting affected functional categories based on downregulated genes in the persistence group (upregulated in the extinction group) where the major boxes represent a category of diseases and function. Illustration of immune cell trafficking and cell-to-cell signaling and interaction are shown in the lower panels. (B) The expression of CD19, CD8A, CD4, CD52, CD2, CD53, CD59, CD47, CD74, and CXCL9 in the extinction (EXT) compared with the persistence (PER) group pre- and post-NAC. ∗p < 0.01, ∗∗p < 0.001, ∗∗∗p < 0.0001. Tree map (hierarchical heatmap) depicting activation of immune cell trafficking (C) and hematological system development and function (D).