Table 1.
Patient demographics.
| Characteristic, n (%) | Total N = 106 |
CHFS 0–2b n = 69 |
CHFS 3–4 n =37 |
p value |
|---|---|---|---|---|
| Patient age in years, mean ± SD | 14.4 ± 3.5 | 14 ± 3.4 | 14.9 ± 3.6 | 0.10 |
| Age at Fontan procedure in years, mean ± SD | 3.5 ± 1.7 | 3.6 ± 2.0 | 3.5 ± 0.9 | 0.28 |
| Duration of Fontan circulation in years, mean ± SD | 10.8 ± 3.6 | 10.5 ± 3.5 | 11.5 ± 3.7 | 0.07 |
| Male, N (%) | 70 (66.0) | 47 (68.1) | 23 (62.2) | 0.67 |
| Race, N (%) | ||||
| Asian | 6 (5.7) | 5 (7.2) | 1 (2.7) | 0.75 |
| Black | 8 (7.5) | 5 (7.2) | 3 (8.1) | |
| White | 35 (33) | 21 (30.4) | 14 (37.8) | |
| Other | 57 (53.8) | 38 (55.1) | 19 (51.4) | |
| Ethnicity, N (%) | ||||
| Hispanic | 73 (68.9) | 47 (68.1) | 26 (70.3) | 0.99 |
| Non-Hispanic | 33 (31.1) | 22 (31.9) | 11 (29.7) | |
| BMI (kg/m2), mean ± SD | 20.8 ± 5.0 | 20.5 ± 5.0 | 21.5 ± 5.0 | 0.16 |
| BMI percentile, mean ± SD | 52.8 ± 33.8 | 51.7 ± 34.3 | 54.9 ± 33.3 | 0.77 |
| Obese, N (%) | 29 (27.4) | 19 (27.5) | 10 (27.0) | 0.99 |
| Dominant ventricle, N (%) | ||||
| Left | 47 (44.3) | 33 (47.8) | 14 (37.8) | 0.51 |
| Right | 55 (51.9) | 34 (49.3) | 21 (56.8) | |
| Undetermined/2-ventricle | 4 (3.8) | 2 (2.9) | 2 (5.4) | |
| Fontan type, N (%) | ||||
| Extra cardiac | 99 (93.4) | 66 (95.7) | 33 (89.2) | 0.24 |
| Lateral tunnel | 7 (6.6) | 3 (4.3) | 4 (10.8) | |
| Fenestration present at biopsy, N (%) | 9 (8.5) | 7 (10.1) | 2 (5.4) | 0.49 |
| Protein-losing enteropathy, N (%) | 9 (8.5) | 6 (8.7) | 3 (8.1) | 0.99 |
| Plastic bronchitis, N (%) | 0 (0) | 0 (0) | 0 (0) | |
Descriptive statistics of the overall cohort and stratified-by-CHFS group. Means and standard deviations reported for continuous variables and tested using a t test. Counts and percentages reported for categorical variables and tested with a Chi-square test.
CHFS, congestive hepatic fibrosis score.