Table 2.
Postmortem indices of two matched cases
| Pathology | Case 1 | Case 2 |
|---|---|---|
| Brain weight | 1,246 g | 1,088 g |
| Atrophy | Mild diffuse | Mild diffuse |
| Neuritic plaques | Moderate-frequent | Moderate-frequent |
| Neurofibrillary tangles | Moderate-frequent | Moderate-frequent |
| NIA-Reagan diagnosis | Intermediate likelihood | Intermediate likelihood |
| Β-amyloid load | 11% | 3.9% |
| Neocortical PHFtau tangle density | 10.4/mm2 | 10.0/mm2 |
| Mesial temporal PHFtau tangle density | 0.66/mm2 | 0.1/mm2 |
| Cerebral amyloid angiopathy | No | Significant |
| Cortical Lewy bodies | 0 | 0 |
| Cerebral infarctions | 0 | three small chronic infarctions |