Table 3.

Multiple Linear Regression Analyses of the Association Between Nocturnal Hypoxemia Measures and Lipid Profiles in Men without Use of Lipid Lowering Therapies or Sleep Disrupting Medications^§ (n=566)

	Unadjusted Model n=566		Covariate Adjusted Model* n=517
	B (SE)	p value	B (SE)	p value
Apnea–Hypopnea Index (AHI)
Triglycerides	0.004(0.003)	0.12	0.003(0.003)	0.36
HDL	-0.001(0.001)	0.24	0.000(0.001)	0.78
LDL	0.001(0.003)	0.64	0.001(0.003)	0.65
Total Cholesterol	0.002(0.003)	0.60	0.001(0.003)	0.64
ODI
Triglycerides	0.006(0.003)	0.069	0.002(0.003)	0.47
HDL	-0.002(0.001)	0.096	0.000(0.001)	0.85
LDL	0.002(0.003)	0.48	0.002(0.003)	0.48
Total Cholesterol	0.002(0.003)	0.48	0.002(0.004)	0.57
AHIREM‡
Triglycerides	0.000(0.003)	0.95	−0.004(0.003)	0.19
HDL	0.000(0.001)	0.81	0.002(0.001)	0.081
LDL	0.001(0.002)	0.66	0.000(0.003)	0.86
Total Cholesterol	0.001(0.003)	0.71	0.000(0.003)	0.99
AHIREM if AHINREM <10/hr
Triglycerides	−0.001 (0.006)	0.88	−0.002 (0.006)	0.79
HDL	0.001 (0.002)	0.96	0.001 (0.002)	0.70
LDL	0.000 (0.005)	0.94	0.000 (0.006)	0.96
Total Cholesterol	0.000 (0.006)	0.98	−0.001 (0.007)	0.94

Notes: *Adjusted for age, smoking, depression, alcohol risk, total sleep time, HbA1c, diet quality, waist circumference. ^§Sleep disrupting medications recorded on the night of the PSG study included benzodiazepines, opiates, nicotine replacement therapy, anti-psychotics, anti-depressants. ^‡AHI_REM: Rapid eye movement sleep (REM) AHI is calculated for participants with at least 30 minutes of REM sleep. In models excluding participants with AHI_NREM<10 unadjusted models n=277; adjusted model n=255.

Abbreviation: AHI_NREM, non-rapid eye movement sleep AHI.