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. 2021 Oct 14;4(10):e2128886. doi: 10.1001/jamanetworkopen.2021.28886

Table 1. Patient Characteristics and Intraoperative Data.

Characteristic No. (%)
Dexmedetomidine group Control group
Total patients, No. 344 331
Age, mean (SD), y 70.1 (5.8) 70.4 (6.5)
Height, mean (SD), cm 163.3 (11.7) 163.0 (14.6)
Weight, mean (SD), kg 60.0 (9.5) 59.3 (9.6)
BMI, mean (SD) 22.3 (2.9) 22.0 (3.0)
Sex
Female 122 (35.5) 108 (32.6)
Male 222 (64.5) 223 (67.4)
Educational level
None 127 (36.9) 115 (34.7)
Primary school 180 (52.3) 162 (48.9)
Secondary school 23 (6.7) 41 (12.4)
College 14 (4.1) 13 (3.9)
ASA classificationa
1 18 (5.2) 12 (3.6)
2 233 (67.7) 231 (69.8)
3 93 (27.0) 88 (26.6)
Method of surgery
Laparoscopic 162 (47.1) 137 (41.4)
Open 182 (52.9) 194 (58.6)
Anatomical site of surgery
Gastric 141 (41.0) 142 (42.9)
Intestinal 102 (29.7) 100 (30.2)
Otherb 101 (29.4) 89 (26.9)
Time, mean (SD), min
Anesthetic 206.08 (73.12) 211.92 (78.44)
Surgical 183.39 (69.87) 190.14 (73.64)
Sufentanil, mean (SD), μgc 41.2 (10.3) 43.1 (8.6)
Remifentanil, mean (SD), μgc 1779.4 (946.7) 2040.0 (1172.5)
Bleeding, median (IQR), mLf 100 (50-200) 100 (50-200)
Crystalloid solution, median (IQR), mLd 1000 (850-1500) 1000 (1000-1500)
Colloidal solution, median (IQR) mLd 500 (500-500) 500 (500-500)
Urine output, median (IQR), mLc,d 300 (200-450) 250 (200-400)

Abbreviations: ASA, American Society of Anesthesiologists; BMI, body mass index (calculated as weight in kilograms divided by height in meters squared).

a

Class 1 indicates normal health; class 2, mild systemic disease; and class 3, severe systemic disease that is not life-threatening.

b

Includes surgery of the liver, gallbladder, pancreas, and appendix.

c

Intraoperative characteristics with significant differences between 2 groups.

d

Values were rounded to the nearest 100 mL.