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. 2021 Oct 14;4(10):e2128886. doi: 10.1001/jamanetworkopen.2021.28886

Table 2. Clinical Postoperative Outcomes.

Outcome Median (IQR) z Score or χ2 value P value
Dexmedetomidine group Control group
Total patients, No. 344 331 NA NA
Primary end point
Time to first flatus, ha 65 (48-78) 78 (62-93) 7.02b <.001
Secondary end points
Time to first feces, ha 85 (68-115) 98 (74-121) 3.47b .001
Time to first oral feeding, ha 76 (52-112) 90 (72-115) 4.55b <.001
Delirium, No. (%)c
Postoperative day 1 41 (11.9) 43 (13.0) 1.13d .57
Postoperative day 2 25 (7.3) 19 (5.7) 0.65d .42
Postoperative day 3 18 (5.2) 12 (3.6) 1.03d .31
Hospital cost, Chinese yuane 40 632 (34 106-47 502) 43 764 (37 102-50 880) 3.81b <.001
Length of stay, d 13 (10-17) 15 (11-18) 2.82b .005

Abbreviation: NA, not applicable.

a

Values were rounded to the nearest hour.

b

z Score.

c

Measured twice daily using the confusion assessment method, which evaluates acute onset and fluctuating course, inattention, disorganized thinking, and altered level of consciousness.

d

χ2 Value.

e

Mean exchange rate for 2018-2019 (years of study period): 1 Chinese yuan = 0.1481 US dollars. Equivalent median for dexmedetomidine group: $6018 (IQR, $5051-$7035). Equivalent median for control group: $6481 (IQR, $5495-$7535).