Table IV.

Primary pathway targets.

Pathway in	Primary targets
Cancer	ABL1, AKT1, AR, CDK2, CREBBP, EGFR, CTNNB1, EP300
Prostate cancer	CDK2, CREBBP, EP300, AKT1, EGFR, MAPK1
Viral carcinogenesis	CDK2, CREBBP, EP300, GRB2, JUN, MDM2, NFKBIA, MAPK1
Estrogen signaling	AKT1, EGFR, ESR1, GRB2, HSPA1A, HSPA1B, HSPA8, HSP90AA1
Thyroid hormone signaling	ACTB, AKT1, CREBBP, CTNNB1, EP300, ESR1, HDAC1
Epstein-Barr virus infection	AKT1, CDK2, CREBBP, EP300, HDAC1, HSPA1A, HSPA1B, HSPA8
PI3K-Akt signaling	AKT1, BRCA1, CDK2, EGFR, FN1, HSP90AA1, HSP90AB1
MAPK signaling	AKT1, ARRB2, EGFR, FLNA, GRB2, HSPA1, AHSPA1B, HSPA8