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. 2021 Sep 30;8(3):e31247. doi: 10.2196/31247

Table 3.

Differences in adjusteda estimates upon multiple comparison at different time points assessed for the primary endpoints, pain, and fatigue sessions.

Time-point comparisons Estimate difference (95% CI) SE t test (df) Bonferroni P value
Numerical Pain Rating Scale score

End of program vs baseline –1.99 (–2.58 to –1.40) 0.30 –6.63 (184) <.001b

6-month follow-up vs baseline –2.72 (–3.31 to –2.13) 0.30 –9.04 (184)

<.001b

6-month follow-up vs end of program –0.73 (–1.32 to –0.14) 0.30 –2.42 (184)

.05b
Foot and Ankle Ability Measure–activities of daily living score

End of program vs baseline 11.60 (7.03 to 16.17) 2.33 5.00 (184) <.001b

6-month follow-up vs baseline 21.70 (17.13 to 26.27) 2.33 9.31 (184)

<.001b

6-month follow-up vs end of program 10.00 (5.43 to 14.57) 2.33 4.31 (184)

<.001b
Foot and Ankle Ability Measure–sports score

End of program vs baseline 19.70 (12.37 to 27.03) 3.74 5.26 (184) <.001b

6-month follow-up vs baseline 37.80 (30.45 to 45.15) 3.75 10.10 (184)

<.001b

6-month follow-up vs end of program 18.10 (10.77 to 25.43) 3.74 4.84 (184)

<.001b
Visual analogue scale for pain score (0-10)

End of program vs baseline –1.16 (–1.64 to –0.67) 0.24 –4.72 (89) <.001b
Visual analogue scale for fatigue score (0-10)

End of program vs baseline 0.07 (–0.47 to 0.61) 0.28 0.24 (89) .81

aAdjusted for age, gender, BMI, days to start treatment, grade of sprain, exercise level, and previous injury.

bStatistically significant at P<.05.