TABLE 6.

Predictors of Visual Outcomes

	Univariate	Multivariate
Visual decline
Maximal dose to optic apparatus ≥10 Gy (vs <10 Gy)	HR = 2.268 95% CI [1.044-4.927], P = .039	HR = 2.370 95% CI [1.086-5.172], P = .03a
Maximal BED to the optic apparatus >36 Gy (vs ≤36 Gy)	HR = 2.373 95% CI [1.086-5.181], P = .030	HR = 2.370 95% CI [1.086-5.172], P = .03a
Single-fraction SRS (vs hypofractionated)	P = .564	–
Nearest distance to optic apparatus (mm)	P = .860	–
In contact with optic apparatus	P = .857	–
Pre-SRS surgery	P = .140	–
Pre-SRS radiation therapy	P = .144	–
Pre-SRS visual impairment	P = .119	–
Treatment volume (cm3)	P = .332	–
Tumor radiological progression	HR = 4.186 95% CI [2.012-8.709], P < .001	HR = 4.340 95% CI [2.070-9.097], P < .001

SD, standard deviation.

^aSeprate multivariate Cox regression models adjusted for signifficant predictors in univariate analyses.