Table 4.
Univariate and multivariate Cox regression analyses of VPS9D1-AS1 for overall survival (OS) of patients in the study cohort (n = 92)
| Variables | OS | ||
|---|---|---|---|
| HR | 95%CI | p value | |
| Univariate analysis | |||
| Age | 1.198 | 0.667-2.149 | 0.545 |
| Gender | 1.176 | 0.583-2.371 | 0.651 |
| Smoking history | 1.293 | 0.725-2.306 | 0.385 |
| Tumor location | 0.976 | 0.605-1.575 | 0.921 |
| Histopathological grade | 2.268 | 1.396-2.384 | 0.001* |
| Tumor invasion depth | 2.075 | 1.403-3.069 | <0.001* |
| Lymph node metastasis | 1.918 | 1.405-2.618 | <0.001* |
| TNM stage | 2.128 | 1.455-3.113 | <0.001* |
| Expression of VPS9D1-AS1 | 4.195 | 2.110-8.341 | <0.001* |
| Multivariate analysis | |||
| Histopathological grade | 0.914 | 0.423-1.977 | 0.820 |
| Tumor invasion depth | 1.167 | 0.495-2.749 | 0.724 |
| Lymph node metastasis | 1.338 | 0.694-2.579 | 0.384 |
| TNM stage | 1.206 | 0.410-3.544 | 0.733 |
| Expression of VPS9D1-AS1 | 3.071 | 1.476-6.391 | 0.003* |