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. 2021 Sep 21;12(22):6676–6684. doi: 10.7150/jca.61591

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Effect of GLI1 on the biological behavior of OS cells after the addition of DDP. After 80 μM DDP addition (A) CCK-8 assays were performed to evaluate cell proliferation. (B, C) Colony formation assay was performed to detect the clone formation capacity. (D, E) Apoptosis of SOSP-9607 and SOSP-9607/CR cells was detected by flow cytometry. (F, G) Scratch area healing in each group after scratched for 0 and 24h (100×). ^*p<0.01 vs. the SOSP-NC group, ^**p<0.01; ^##p<0.01 vs. the SOSP/CR-NC group, ^###p<0.001.