Table 2.

Association of baseline characteristics with PD conversion.

	Unadjusted HR (95% CI)	Adjusted HR (95% CI) &
Age	1.34 (1.12–1.63)**	1.30 (1.09–1.54)**
Current smoking	0.78 (0.62–0.98)*	0.81 (0.66–0.99)*
Daily drinking	1.27 (1.02–1.59)*	1.25 (1.01–1.50)*
WMHs	1.30 (1.04–1.62)**	1.28 (1.02–1.59)*
MetS	1.74 (1.38–2.19)**	1.69 (1.29–2.03)**
Central obesity	1.04 (0.83–1.30)	1.02 (0.81–1.27)
High blood pressure	1.24 (0.99–1.54)	1.23 (0.97–1.51)
High fasting plasma glucose	1.31 (1.05–1.63)*	1.29 (1.03–1.60)*
Hypertriglyceridemia	1.22 (0.98–1.52)	1.20 (0.96–1.50)
Low HDL-C	1.19 (0.95–1.45)	1.16 (0.92–1.41)
Number of MetS components
0
1	0.79 (0.61–1.02)	0.81 (0.63–1.01)
2	0.97 (0.73–1.28)	0.98 (0.75–1.26)
3	1.40 (1.05–1.86)*	1.39 (1.04–1.84)*
4-5	1.77 (1.32–2.38)**	1.75 (1.30–2.36)**

BMI, body mass index; CI, confidence interval; HDL-C, high density lipoprotein cholesterol; HR, hazard ratio; LDL-C, low density lipoprotein cholesterol; MetS, metabolic syndrome; PD, Parkinson's disease; WMHs, white matter hyperintensities.

^&The model is adjusted for age, daily drinking, current smoking, metabolic syndrome, and WMHs.

^* P < 0.05;

^**P < 0.01.