Table 3.

MetS with symptom progression of MPS.

	Bradykinesia adjusted HR (95% CI) &	Rigidity adjusted HR (95% CI) &	Tremor adjusted HR (95% CI) &	Gait/balance adjusted HR (95% CI) &
MetS	1.85 (1.43–2.34)**	1.36 (1.19–1.57)*	1.98 (1.73–2.32)**	1.66 (1.25–2.11)**
Central obesity	1.04 (0.91–1.15)	1.01 (0.90–1.12)	1.06 (0.93–1.16)	1.03 (0.89–1.17)
High blood pressure	1.29 (1.10–1.58)*	1.18 (0.89–1.22)	1.31 (1.12–1.65)*	1.22 (0.95–1.34)
High fasting plasma glucose	1.28 (1.07–1.55)*	1.26 (1.04–1.52)*	1.40 (1.12–1.69)*	1.17 (1.02–1.49)*
Hypertriglyceridemia	1.14 (1.01–1.48)	1.08 (0.93–1.38)	1.17 (1.06–1.51)	1.05 (0.95–1.41)
Low HDL-C	1.07 (0.95–1.43)	1.04 (0.91–1.35)	1.15 (0.98–1.47)	1.12 (0.93–1.28)
Number of MetS components
1 component	1.06 (0.93–1.16)	1.04 (0.90–1.14)	1.02 (0.88–1.12)	1.08 (0.96–1.19)
2 components	1.17 (0.96–1.29)	1.06 (0.91–1.22)	1.13 (0.89–1.19)	1.15 (0.94–1.22)
3 components	1.54 (1.19–1.95)*	1.17 (0.98–1.52)	1.64 (1.28–2.06)*	1.46 (1.12–2.01)*
4-5 components	1.99 (1.61–2.56)**	1.45 (1.18–1.93)**	2.24 (1.63–2.89)**	2.05 (1.82–2.64)**

CI, confidence interval; HDL-C, high density lipoprotein cholesterol; HR, hazard ratio; MetS, metabolic syndrome; WMHs, white matter hyperintensities.

^&The model is adjusted for age, daily drinking, current smoking, metabolic syndrome, and WMHs.

^* P < 0.05;

^**P < 0.01.