. Author manuscript; available in PMC: 2022 Mar 15.

Published in final edited form as: Acta Biomater. 2021 Jan 11;123:197–207. doi: 10.1016/j.actbio.2021.01.006

Table 2:

Results of identifiability analysis. A γ value ≤ 0.05 indicates that the parameter was successfully identified, where a larger value indicates lack of identification.

Model	Criteria	$Identifiability parameter γ := \| \frac{median (p_{fit)} - p_{0}}{p_{0}} \|$							# of parameters identified

		Matrix			Fibers

		*E_NH*	*ν_NH*
IsoComp	1	0.013 ^*	0.249						1/2
IsoComp	1&2	0.001 ^*	0.046 ^*						2/2

		*E_HM*	*ν_HM*	*β_HM*
IsoTens	1	0.015 ^*	0.364	4.924					1/3
IsoTens	1&2	0.029 ^*	0.035 ^*	0.250					2/3

		*E_NH*	*ν_NH*		*E_f*	*β_f*	λ₀
XIsoComp	1	0.055	0.114		4.115	4.998	0.003 ^*		1/5
XIsoComp	1&2	0.034 ^*	0.127		4.036	6.105	0.004 ^*		2/5

		*E_HM*	*ν_HM*	*β_HM*	*E_f*	*β_f*	λ₀
XIsoTens	1	3.200	0.229	4.656	0.015 ^*	1.617	0.003 ^*		2/6
XIsoTens	1&2	0.684	0.009 ^*	3.333	0.012 ^*	1.606	0.003 ^*		3/6

		*E_NH*	*ν_NH*		*E_f*	*β_f*	λ₀	*k_VM*
OrthoComp	1	0.023 ^*	0.081		4.110	4.360	0.001 ^*	0.158	2/6
OrthoComp	1&2	0.021 ^*	0.007 ^*		0.128	3.967	0.00003 ^*	0.032 ^*	4/6

γ ≤ 0.05