Skip to main content
. 2021 Oct 15;23:259. doi: 10.1186/s13075-021-02633-5

Table 2.

Overrepresented MSigDB hallmark signatures in SSc vs. control comparison in the PBC gene expression dataset

MSigDB ID Size Direction PValue %FDR Description
M5911 75 Up 8E−13 4E−9 INTERFERON_ALPHA_RESPONSE
M5913 133 Up 9E−08 2E−4 INTERFERON_GAMMA_RESPONSE
M5932 96 Up 0.0003 0.6 INFLAMMATORY_RESPONSE
M5897 37 Up 0.0014 1.8 IL6_JAK_STAT3_SIGNALING
M5928 32 Down 0.0034 3.4 MYC_TARGETS_V2