Table 3. Phenotypic antibiotic susceptibilities and associated genetic resistance markers in isolates from patients with Vibrio spp. infections, Germany, 2018 and 2019 (n = 48 isolates).
| Antibiotic | Phenotypic susceptibility (n = 47) | Resistance detected by WGS (n = 47) | |||||
|---|---|---|---|---|---|---|---|
| Resistant | Intermediate | Gene or mutation | Positive | ||||
| n | % | n | % | n | % | ||
| AMK | 2 | 4.3 | 11 | 23.4 | NA | 0 | 0 |
| AMP | 6 | 12.8 | 3 | 6.4 | blaCARB-7 | 2 | 4.3 |
| AMC | 1 | 2.1 | 2 | 4.3 | blaCARB-18, blaCARB-21, blaCARB-26, blaCARB-30, blaCARB-42 | 7 | 14.9 |
| MEM | 0 | 0 | 0 | 0 | varG | 15 | 31.9 |
| TET | 0 | 0 | 0 | 0 | tet 34, tet 35 | 18 | 38.3 |
| GEN | 1 | 2.1 | 0 | 0 | NA | 0 | 0 |
AMC: amoxicillin-clavulanic acid; AMK: amikacin; AMP: ampicillin; GEN: gentamicin; MEM: meropenem; NA: not applicable; TET: tetracycline; WGS: whole genome sequencing.