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. 2021 Jun 26;16(19):3044–3059. doi: 10.1002/cmdc.202100282

Figure 4.

Figure 4

Checkerboard assays: A) CPX MIC reduction against SA‐1199B in the presence of increasing (from 0.19 to 6.25 μg/mL) concentrations of derivatives 8 ac, 10 a, 12 b, 12 c, 13 a and 13 b and reference compound 1. B) CPX MIC reduction against SA‐K2378 in the presence of increasing (from 0.19 to 12.5 μg/mL) concentrations of derivatives 8 b, 8 c, 12 c and 13 a. Assays performed in duplicate.