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. 2021 Jun 24;21(7):2350–2363. doi: 10.1111/1755-0998.13442

TABLE 2.

Definitions of each metric used to assess a selection detection method's accuracy with the simulated data

Accuracy metric Definition Equationa
True discovery rate The proportion of all simulated loci identified as outliers that were actually under selection (i.e., QTL loci)
OselOsel+Onet
True positive rate The proportion of loci under selection (i.e., QTL loci) correctly identified as an outlier
OselTotalsel
False positive rate The number of neutral loci incorrectly identified as under selection (false positive outliers) divided by the number of retained polymorphic neutral SNPs
OnetTotalnet
False discovery rate The proportion of outlier SNPs that were false positives (i.e., simulated neutral loci) (Lotterhos & Whitlock, 2014)
OnetOsel+Onet
False negative rate The proportion of polymorphic QTLs that were not identified as outliers (and thus not identified as under selection)
TotalselOselTotalsel
a

Osel, outer loci truly under selection; Onet, false positive neutral outlier loci; Totalsel, total number of polymorphic loci under selection; Totalnet, total number of polymorphic neutral loci.