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. 2021 Oct 1;12:700612. doi: 10.3389/fendo.2021.700612

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Copyright © 2021 Höppner, Lais, Roll, Wegener-Panzer, Wieczorek, Högler and Grasemann

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Laboratory parameters and calcium-affecting treatments over the first 150 respectively 240 days in Patient 1 Panel (A) and Patient 2 Panel (B). Vitamin D3 was provided orally/once daily. Cinalcacet was started in patient 2 on day 26 of life at 20 mg/m² body surface (5mg) daily and increased on day 137 of life based on increased body weight and elevated calcium levels (to 6mg). Age-appropriate normative range is indicated by the grey bar for calcium, PTH and total serum alkaline phosphate (TSAP) levels; Red arrow: estimated date of delivery.