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. 2021 May 2;22(19):2848–2856. doi: 10.1002/cbic.202100127

Figure 4.

Figure 4

NMR high‐resolution structure of a parallel quadruplex (−p−p−p) formed by a c‐myc promoter sequence (PDB 6NEB). [49] An adenine base at the 3’‐end of the long 6‐nt central propeller loop is Hoogsteen hydrogen‐bonded to a 5’‐flanking T residue (both shown in magenta) and stacks as part of an ATG triad onto the outer G‐tetrad; G‐core, overhang sequences and propeller loops are colored grey, yellow, and cyan, respectively.