Figure 4.
NMR high‐resolution structure of a parallel quadruplex (−p−p−p) formed by a c‐myc promoter sequence (PDB 6NEB). [49] An adenine base at the 3’‐end of the long 6‐nt central propeller loop is Hoogsteen hydrogen‐bonded to a 5’‐flanking T residue (both shown in magenta) and stacks as part of an ATG triad onto the outer G‐tetrad; G‐core, overhang sequences and propeller loops are colored grey, yellow, and cyan, respectively.