TABLE 1.

Change in body weight at 52 weeks overall and among patients reporting or not reporting ≥1 TEAE of nausea, vomiting or diarrhoea

Dulaglutide dose (mg)	Change in weight from baseline (kg)
	Total	Patients reporting no GI TEAEs a	Patients reporting ≥1 GI TEAEs a
	N = 1809	N = 1361	N = 448
1.5	−3.5 (0.21)	−3.6 (0.24)	−3.1 (0.47)
3.0	−4.3 (0.21)	−4.1 (0.24)	−5.0 (0.44)
4.5	−5.0 (0.21)	−5.0 (0.24)	−5.0 (0.42)

Abbreviations: GI, gastrointestinal; LSM, least‐squares mean; MMRM, mixed model for repeated measures; TEAE, treatment‐emergent adverse event; SE, standard error.

^a Nausea, vomiting and/or diarrhoea. All values presented as LSM (SE), MMRM. N, patients with baseline and at least one postbaseline weight measurement.