TABLE 4.
Minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) of CFHE1, CFHE2 and reference compounds against the Gram‐negative Pseudomonas aeruginosa ATCC 9027 and Escherichia coli ATCC 10536 bacteria, and the yeast Candida albicans ATCC 10231. Results (μg/ml) were expressed as mean ± S.D. of three independent experiments in triplicate (n = 3)
| CFHE1 | CFHE2 | Reference compound | |
|---|---|---|---|
| MIC (μg/ml) | |||
| Gram‐negative | Tobramycin | ||
| P. aeruginosa ATCC 9027 | NA | NA | 0.23 ± 0.01 |
| E. coli ATCC 10536 | 2500 * | 1250 * | 0.48 ± 0.02 |
| MFC (μg/ml) | |||
| Yeast | Caspofungin | ||
| C. albicans ATCC 10231 | NA | NA | 0.061 ± 0.00 |
Abbreviation: NA, not active.
*
p < .001 versus tobramycin.