Table 2.

Intra-day and inter-day accuracy and precision of eight TKIs from the assay samples.

		Intra-day		Inter-day
Analyte	Nominal Concentration (nM)	Accuracy (bias, %)	Precision (CV, %)	Accuracy (bias, %)	Precision (CV, %)
Erlotinib	400	−4.2	3.1	−7.5	4.2
	50	5.2	7.3	9.6	6.5
	6.25	9.2	10.1	−0.6	14.9
Sorafenib	1600	0.8	3.0	1.4	2.6
	200	9.3	5.4	13.7	4.8
	25	15.0	6.5	12.3	7.5
Sunitinib	800	−12.0	2.5	−12.2	2.7
	100	7.8	8.8	11.3	5.6
	12.5	14.6	4.7	13.3	5.6
Dasatinib	1600	−1.5	3.7	−3.2	3.4
	200	5.8	4.0	8.3	4.4
	25	8.7	11.7	1.1	12.7
Lapatinib	1600	−11.6	7.2	−10.1	6.1
	200	−0.2	7.0	0.6	9.6
	25	0.4	14.3	0.8	10.4
Nilotinib	1600	−6.5	6.2	−10.7	6.2
	200	6.5	6.5	6.7	6.1
	25	6.6	7.5	−1.8	13.1
Pazopanib	800	1.5	4.7	−9.4	9.5
	100	0.9	5.6	−6.1	7.4
	12.5	8.6	13.1	−7.1	16.7
Axitinib	800	−5.1	3.8	−8.8	5.4
	100	0.9	5.3	0.0	3.8
	12.5	4.5	7.8	−0.9	11.2