Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Similarity‐guided screening of a focused library. Compounds were selected based on the former screening hit I:47 with variations in the three displayed structure motifs. KD values were determined for 79 positive hits showing a visible shift of absorbance maximum at concentrations ≤20 μM. MIC50 values were determined for 29 compounds, which showed inhibition ≥60 % at 10 μM.
