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. 2021 Jun 22;16(18):2786–2801. doi: 10.1002/cmdc.202100283

Figure 5.

Figure 5

Effect of CYP121 substrate cYY on the growth of M. bovis BCG and its inhibition by I:47. The addition of 50 μM cYY accelerated the growth of M. bovis BCG (B). The resulting growth enhancement of cYY (A, grey striped bar) can be reversed through the CYP121 inhibitor I:47 in a concentration‐dependent manner (grey bars) in accordance to its growth‐inhibiting effect (black bars).