Scheme 2.
Reagents and conditions: (ia) method D a): TBDMSCl, imidazole, CH2Cl2, rt, 16 h; (ib) method D b): TBDMSCl, NaH, CH2Cl2, 0 °C→ rt, 16 h; (ii) method E: nBuLi, B(OiPr)3, THF, −78 °C→rt, 3 h; (iii) method F: TBAF, K2HPO4, THF, rt, 16 h.
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