Table 1.
KD and MIC50 values of compounds showing better activity than I:47.
|
| |||
|---|---|---|---|
|
Compound |
KD±STD [μM] |
MIC50 [mg/L] |
MIC50 [μM] |
|
Econazole |
2.8±0.2[a] |
2.6 |
12.7 |
|
I:47 |
5.4±1.0[a] |
1.4 |
4.0 |
|
L10 |
2.9±0.4 |
0.9 |
2.6 |
|
L14 |
6.4±0.9 |
0.9 |
2.7 |
|
L15 |
4.3±0.8 |
0.7 |
1.8 |
|
L21 |
5.9±0.6 |
0.5 |
1.5 |
|
L44 |
5.6±0.9 |
0.8 |
2.4 |
|
L45 |
12.6±2.0 |
1.2 |
3.4 |
|
L46 |
9.2±2.0 |
1.0 |
2.9 |
|
L76 |
6.6 ±1.0 |
1.1 |
3.2 |
|
L78 |
0.6±0.2 |
0.8 |
2.4 |
|
L94 |
4.7±0.8 |
1.1 |
3.3 |
[a] Determined previously. [20] KD±STD was calculated from four biological replicates.