Table 2. Hematopathological features of DLBCL-IV patients.

Patient No.	Diagnostic materials	Diagnostic sites and rate of intravascular invasion (%)	CD5	CD10	Bcl-2	Bcl-6	IRF4/ MUM-1	CD29	CD54	Ki-67 (%)	PD-L1 score
1	Biopsy Autopsy	(Biopsy) Skin (40) (Autopsy) Lungs, pancreas, stomach, esophagus, large intestine, urinary bladder (100), liver, kidneys (80), spleen (50), bone marrow (<1)	-	-	+	+	+	-	-	85	0
2	Surgery	Ovary (80)	-	-	+	-	+	-	+	45	2
3	Biopsy	Skin (70)	-	-	+	+	+	-	+/-*	50	1
4	Biopsy	Skin (100), bone marrow (<1)	+	-	+	-	+	-	-	NA	0
5	Biopsy	Skin (50), bone marrow (0)	+	-	-	+	+	+	-	93	1
6	Autopsy	Lungs, kidneys, adrenal glands, stomach (100), liver (85), spleen, bone marrow (0)	-	-	+	-	+	-	-	75	0
7	Autopsy	Lungs, liver, adrenal glands, stomach, pancreas, esophagus, small intestine, large intestine, lymph nodes (100), breast (10), bone marrow (0)	-	+	+	+	+	-	-	50	1
8	Autopsy	Lungs, liver, adrenal glands, stomach, pancreas, esophagus, small intestine, large intestine, heart, gallbladder, urinary bladder, testis (100), kidney (85), lymph nodes (15), spleen, bone marrow (<1)	+	-	+	-	-	-	-	NA	0
9	Autopsy	Kidney, adrenal glands, stomach, heart, uterus (100), lungs (60), liver (20), lymph nodes (<1), spleen, bone marrow (0)	+	-	+	-	+	+	+	50	2
10	Autopsy	Kidney, stomach, pancreas, heart, gallbladder, small intestine, large intestine, urinary bladder, thyroid gland, uterus, fallopian tubes (100), ovaries (80), lungs, adrenal glands (70), liver (50), spleen, lymph nodes (<1), bone marrow (0)	+	-	+	+	+	-	+	40	2
11	Autopsy	Lungs, kidneys, stomach, urinary bladder, heart, thyroid gland, prostate, brain (100), adrenal glands (80), liver (50), lymph nodes (0)	-	+	+	-	-	-	+	70	0

Abbreviations: DLBCL-IV, diffuse large B-cell lymphoma with significant intravascular invasion; NA, not available; PD-L1, programmed death-ligand 1.

* The extravascular, but not intravascular, lymphoma cells were negative for CD54.